By Kristina Fiore
Source Medpagetoday
A 15-day course of the antiviral nirmatrelvir-ritonavir (Paxlovid) didn’t improve symptoms of long COVID, according to a randomized controlled trial that was stopped early for lack of efficacyopens in a new tab or window.
The STOP-PASC trial showed no difference in improvement on a combined outcome of fatigue, brain fog, shortness of breath, body aches, and gastrointestinal and cardiovascular symptoms for nirmatrelvir-ritonavir compared with placebo-ritonavir over 10 weeks, Upinder Singh, MD, of Stanford University, and colleagues reported in JAMA Internal Medicineopens in a new tab or window.