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SARS‑CoV‑2 nucleocapsid protein promotes self‑deacetylation by inducing HDAC6 to facilitate viral replication

by | 8月 12, 2024 | 科學抗疫, 病毒、病理生理學

對不起,此内容只適用於English

By Arpita Mukherjee et al.

Source BMC

Abstract

Background

The global outbreak of COVID-19 caused by the SARS-CoV-2 has led to millions of deaths. This unanticipated emergency has prompted virologists across the globe to delve deeper into the intricate dynamicity of the host-virus interface with an aim to identify antiviral targets and elucidate host and viral determinants of severe disease.

Aim

The present study was undertaken to analyse the role of histone deacetylase 6 (HDAC6) in regulating SARS-CoV-2 infection.

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