By Judy George
Source Medpagetoday
Healthier lifestyle behaviors in midlife were linked with better outcomes in people with genetic predisposition for age-related brain diseases, longitudinal data from the U.K. Biobank showed.
Over about 12 years of follow-up, each 5-point improvement in Brain Care Score was tied to a reduced risk of dementia (HR 0.82, 95% CI 0.78-0.85), stroke (HR 0.70, 95% CI 0.68-0.73), and late-life depression (HR 0.65, 95% CI 0.63-0.67), reported Christopher Anderson, MD, MMSc, of Massachusetts General Hospital in Boston, and colleagues.
For all three outcomes, incidence was higher among people with high genetic risk. However, this increased risk was offset for individuals with higher Brain Care Scores, the researchers said in Neurologyopens in a new tab or window.
Read more https://www.medpagetoday.com/neurology/dementia/112816