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Hormonal Contraception Linked to Increased Breast Cancer Risk in BRCA1 Carriers

by | Oct 7, 2024 | Cancer, Cancer

By Charles Bankhead

Source Medpagetoday

Carriers of the BRCA1 cancer gene had a significantly increased risk of breast cancer if they used hormonal contraception (HC), pooled cohort data showed.

Breast cancer risk increased by 29% in BRCA1 carriers who reported any use of HC during at least one 12-month continuous period. The risk also increased with duration of HC use, but separate analyses showed no increased risk associated with current use within the past year, 1-5 years in the past, 6-10 years before, or more than 10 years.

The analysis showed no evidence of increased breast cancer risk for BRCA2 carriers who used HC, reported Kelly-Anne Phillips, MD, MBBS, of Peter MacCallum Cancer Center in Melbourne, Australia, and co-authors in the Journal of Clinical Oncologyopens in a new tab or window.

Read more https://www.medpagetoday.com/hematologyoncology/breastcancer/112289