Transplacental SARS-CoV-2 protein ORF8 binds to complement C1q to trigger fetal inflammation

by admin | Oct 10, 2024 | Clinical Manifestations, Transmission, Epidemiology, Virus, Pathophysiology, Scientific reports, Self-defence againsts infection, Virology, Pathophysiology

By Tamiris Azamor et al.

Source The EMBO press

Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2 infections can trigger immune responses in a pregnant individual that may cause serious inflammatory responses in the developing fetus.

It is indeed possible for only a small part of a virus to slip through and affect a pregnancy, including ORF8