SARS-CoV-2 hijacks host CD55, CD59 and Factor H to impair antibody-dependent complement-mediated lysis
By Laura Gebetsberger et al. Source Taylor&Francis Online SARS-CoV-2 hijacks host CD55, CD59 and Factor H to impair antibody-dependent...
Virology, Pathophysiology
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia
By Xiaowen Huang et al. Source BMC 新冠敗血，腦病叢生 48.9 million people suffer from sepsis each year, and 19.7% of global deaths are related to this...
Virological characteristics of the SARS-CoV-2 XEC variant
By Yu Kaku et al. Source bioRxiv XEC 混變，將成主流 Virological characteristics of the SARS-CoV-2 XEC variant : data suggests that XEC will be a...
Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19
By August F. Jernbom et al. Source Nature Researchers found on the new-onset autoantibody repertoire in 525 healthcare workers and hospitalized...
Tissue resident memory T cells contribute to protection against heterologous SARS-CoV-2 challenge
By Abby Odle et al. Source JCI Insight This study found that mice previously infected with recent SARS-CoV-2 variants like Omicron were protected...
Modulation of the α7 nicotinic acetylcholine receptor by the “neurotoxin-like region” of the SARS-CoV-2 spike protein is selective, allosteric, and concentration- specific (a role in aggression and anxiety?)
Modulation of the α7 nicotinic acetylcholine receptor (which has a role in the modulation of behavior like aggression, mood, and impulsivity) by the...
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain
By Cordelia Dunai et al. Source Frontiers 心臟感染，遙感腦炎 Latest findings suggest that a primarily pulmonary inflammatory process is rapidly associated...
Characterization of three-nucleate Rhizoctonia AG-E based on their morphology and phylogeny
By Ewa Moliszewska rt al. Source Nature 中國新冠大流行，過敏性鼻炎加增 From a China study using local big data of patients with allergic rhinitis (AR) in from 2018...
Elevated serum mtDNA in COVID‑19 patients is linked to SARS‑CoV‑2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
By Anna Shteinfer‑Kuzmine et al. Source Springer Link Abstract Mitochondria dysfunction is implicated in cell death, inflammation, and autoimmunity....
Transplacental SARS-CoV-2 protein ORF8 binds to complement C1q to trigger fetal inflammation
By Tamiris Azamor et al. Source The EMBO press Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2...