Anti-Nucleocapsid and Anti-Spike Antibody Trajectories in People with Post-Covid Condition versus Acute-Only Infections: Results from the Virus Watch Prospective Cohort Study

Background Early evidence suggests that people with Post-Covid Condition (PCC) may demonstrate aberrant immune responses post-infection; however, serological follow-up studies are currently limited. We aimed to compare SARS-CoV-2 serological responses to primary infection and vaccination in people who developed PCC versus those with an acute infection only.