Persistent Activation of Chronic Inflammatory Pathways in Long Covid
By Malika Aid et al. Source bioRxiv Abstract Long Covid, or Post-Acute Sequelae of COVID-19 (PASC), involves a spectrum of chronic symptoms...
Virology, Pathophysiology
A Potentially Fatal New COVID-Related Syndrome Has Emerged
By Benjamin Taub Source iflscience Arare yet deadly autoimmune disorder appears to be on the rise in the north of England, and new research...
Brain abnormalities in survivors of COVID-19 after 2-year recovery: a functional MRI study
By Yimiao Zhao et al. Source The Lancet Background A variety of symptoms, particularly cognitive, psychiatric and neurological symptoms, may persist...
Coronavirus disease 2019 and its impact on the cognition of older adults: Unraveling the role of inflammation
By Shahrzad Mortazavi et al. Source Sciencedirect Abstract Background The Coronavirus Disease 2019 (COVID-19) pandemic significantly impacted the...
Evidence that the SARS-CoV-2 S protein undergoes a conformational change at the Golgi Complex that leads to the formation of virus neutralising antibody binding epitopes in the S1 protein subunit
By Yanjun Wu et al. Source bioRxiv Abstract Recombinant SARS-CoV-2 S protein expression was examined in Vero cells by imaging using the human...
An FDA-approved assay platform can detect biomarkers of neuronal and glial injury in the blood of COVID-19 patients
By Alexander V. Glushakov et al. Source medRxiv Abstract Employing assays approved by the U.S. Food and Drug Administration (FDA) to assist in...
An amyloidogenic fragment of the SARS CoV-2 envelope protein promotes serum amyloid A misfolding and fibrillization
By Asal Nady et al. Source biorxiv ABSTRACT SARS CoV-2 infection can affect a surprising number of organs in the body and cause symptoms such as...
Blood transcriptomic analyses reveal persistent SARS-CoV-2 RNA and candidate biomarkers in post-COVID-19 condition
By Soraya Maria Menezes et al. Source The Lancet With an estimated 65 million individuals affected by post-COVID-19 condition (also known as long...
Pertussis upsurge, age shift and vaccine escape post-COVID-19 caused by ptxP3 macrolide-resistant Bordetella pertussis MT28 clone in China: a genomic epidemiology study
By Pan Fu et al. Source MedRxiv Summary Background The upsurge of pertussis post-COVID-19 and expansion of macrolide-resistant Bordetella...
A generalized framework to identify SARS-CoV-2 broadly neutralizing antibodies
By Fanchong Jian et al. Source MedRxiv Abstract Monoclonal antibodies (mAbs) targeting the SARS-CoV-2 receptor-binding domain (RBD) showed high...