Tissue resident memory T cells contribute to protection against heterologous SARS-CoV-2 challenge
By Abby Odle et al. Source JCI Insight This study found that mice previously infected with recent SARS-CoV-2 variants like Omicron were protected...
Virology, Pathophysiology
Modulation of the α7 nicotinic acetylcholine receptor by the “neurotoxin-like region” of the SARS-CoV-2 spike protein is selective, allosteric, and concentration- specific (a role in aggression and anxiety?)
Modulation of the α7 nicotinic acetylcholine receptor (which has a role in the modulation of behavior like aggression, mood, and impulsivity) by the...
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain
By Cordelia Dunai et al. Source Frontiers 心臟感染，遙感腦炎 Latest findings suggest that a primarily pulmonary inflammatory process is rapidly associated...
Elevated serum mtDNA in COVID‑19 patients is linked to SARS‑CoV‑2 envelope protein targeting mitochondrial VDAC1, inducing apoptosis and mtDNA release
By Anna Shteinfer‑Kuzmine et al. Source Springer Link Abstract Mitochondria dysfunction is implicated in cell death, inflammation, and autoimmunity....
COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type
By James R. Hilser et al. Source AHAjournals People with whatever COVID-19 infection were twice as likely to have a major cardiac event, such as...
Bison, Elk, and Other Captive Wildlife Species Humoral Immune Responses against SARS-CoV-2
By Mehrnaz Ardalan et al. Source MDPI This study investigated SARS-CoV-2 seroprevalence in bison, elk, and captive wildlife across the U.S. using...
Emerging signs of Alzheimer-like tau hyperphosphorylation and neuroinflammation in the brain post recovery from COVID-19
By Xuetao Qi et al. Source Wiley 新冠無病徵，腦退化湧現 Emerging signs of ALZHEIMER'S-LIKE PATHOLOGY in the BRAIN of INDIVIDUALS who had RECOVERED from...
RNA‐Seq analysis of human heart tissue reveals SARS‐CoV‐2 infection and inappropriate activation of the TNF‐NF‐κB pathway in cardiomyocytes
By Kirtan Dave et al. Source Nature Abstract The negative impact of SARS-CoV-2 virus infection on cardiovascular disease (CVD) patients is well...
COVID Preventive Drug Should Work Against Circulating Variants, FDA Now Says
By Katherine Kahn Source Medpagetoday The FDA has determined that the monoclonal antibody pemivibart (Pemgarda) is likely to be effective against...
Oncogenic potential of SARS-CoV-2— targeting hallmarks of cancer pathways
By Aishwarya Jaiswal et al. Source BMC Abstract The 2019 outbreak of SARS-CoV-2 has caused a major worldwide health crisis with high rates of...