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Abnormal brain activation during working memory task in individuals with post-COVID neuropsychiatric

by | Jun 10, 2024 | Brain, Evidence-Based Research in Western Medicine Clinical Practice, Scientific reports

Source DiscoverMedNews

More than two years after the global COVID-19 pandemic, it is clear that infection with severe acute respiratory syndrome coronavirus type-2 (SARS-CoV-2) can lead to a new disease called post-acute COVID-19 syndrome (PASC) or long COVID. In the post-acute phase of COVID-19, there is an increased risk of neurologic sequelae, affecting the central nervous system (CNS) or the peripheral nervous system (PNS). In this study, researchers from the United States used blood-oxygenation-dependent functional MRI (BOLD-fMRI) to investigate whether patients with post-COVID neuropsychiatric symptoms had abnormal brain activation during a working memory task. They also examined the possible relationships between abnormal brain activation and performance on three NIH-Toolbox (NIHTB) batteries for cognitive, emotional, and motor functions.

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