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A longitudinal study on SARS-CoV-2 seroconversion, reinfection and neutralisation spanning several variant waves and vaccination campaigns, Heinsberg, Germany, April 2020 to November 2022

by | Jun 27, 2024 | Evidence-Based Research in Western Medicine Clinical Practice, Scientific reports

By Bianca Schulte et al.

Source eurosurveillance

We wanted to better understand the long-term immune responses against SARS-CoV-2 in the population, and how they were influenced by the COVID-19 vaccination campaigns and the emergence of new SARS-CoV-2 variants. We studied a small German community over 31 months, which had experienced a large COVID-19 outbreak during the early pandemic in Germany.

We estimated the rate at which immunity against the virus fades in the population. Our study also demonstrated the consequences of SARS-CoV-2´s changeability, by showing that neither three vaccinations nor infections with earlier variants, or a combination of both, protects from infection with the more recent Omicron variants of the virus.

Read more https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2024.29.26.2300659#header